ea0031oc4.4 | Obesity, metabolism and bone | SFEBES2013
Papacleovoulou Georgia
, Abu-Hayyeh Shadi
, Nikolopoulou Evanthia
, Ovadia Caroline
, Nikolova Vanya
, Jarvelin Marjo-Riitta
, Jansen Eugene
, Albrecht Christiane
, Marin Jose J G
, Knisely Alex S
, Williasmon Catherine
Epidemiological studies have identified the intrauterine environment as a major contributor to increased rates of metabolic disease in adults, but the underlying mechanisms are poorly understood. Intrahepatic cholestasis of pregnancy (ICP) is a common liver disease of pregnancy that affects 0.52% pregnant women and is characterised by increased bile acid (BA) levels in the maternal serum. The influence of ICP on the metabolic health of offspring is unknown.<p class="...